You will also be required to ensure that the laboratories are maintained as a safe, clean and professional environment, to provide a crucial interface between researchers, University departments and external contractors. In collaboration with the STRUBI Senior Management Team and HWB Facilities Team, you will support the delivery of laboratory development plans, ensuring appropriate facilities and lab provision to meet the demands of world-leading research.

 

You will act as the designated building Departmental Safety Officer (DSO) for STRUBI ensuring that departmental safety plans and documentation are reviewed annually, revised where appropriate, and copies supplied to relevant central University service departments. You will monitor the working environment within STRUBI, ensuring compliance with health and safety regulation and OU policies, reporting unsafe, unhealthy or unsatisfactory conditions to the STRUBI Deputy Business Manager (DBM), Business Manager and Senior Building and Facilities Manager (SBFM).

 

It is essential that you are educated to A levels or an equivalent level 3 qualifications (such as level 3 NVQ; or national diploma), alongside experience of running a biomedical laboratory environment as well as implanting Health & Safety procedures, regulatory compliance and knowledge of Health & Safety legislation within a scientific workplace. You will have strong problem-solving capability, with the ability to maintain a flexible and collaborative approach.

 

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

 

This position is offered on a permanent, full-time basis.

 

Only applications received before 12 midday on Thursday, 30 April 2026 will be considered. Please quote 184986 on all correspondence.

 

In this role, you will manage your own research within the project, leading experimental design, protein production, purification, and structural, biophysical and cellular characterisation of multi-subunit protein complexes. You will independently collect and analyse cryo-EM and X-ray crystallography data, adapt and develop new protocols, and contribute to research publications, grant applications, and presentations at national and international conferences. You will collaborate closely with internal and external partners, including the Diamond Light Source synchrotron, and play a valuable role in advising colleagues and contributing to the supervision of students.

 

You will hold (or be close to completing) a PhD in a relevant discipline, such as chemistry, biology or a related field. You must have hands-on experience structural biology of extracellular and membrane proteins using single particle cryo-EM and X-ray crystallography. You will have demonstrable expertise, data collection and processing of X-ray data (including synchroton data collection), signle particle cryo-EM data using cutting edge microscopes such as Glacios or Krios.

 

You should be able to design and execute experiments independently, solve technical challenges, and analyse complex structural and biochemical data. Strong communication skills both written and verbal are essential, alongside evidence of contributing to research publications and presenting scientific results. You will be highly organised, capable of managing multiple aspects of a project simultaneously, and motivated to contribute ideas, develop new research directions, and support colleagues within a collaborative research environment.

 

Why Siebold Lab & this project?

•         Work within a leading structural biology team focusing on membrane protein complexes, signalling and receptor pharmacology.

•         Benefit from access to top-tier cryo-EM facilities and vibrant collaborations across the UK, including the UK Diamond Light Source synchrotron, and internationally.

•         Target fundamental mechanisms with clear translational relevance to cancer, and other developmental and neurological diseases.

 

Applications for this vacancy should be made online, and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

 

This position is offered full time on a fixed term contract until 30 September 2028 and is funded by Cancer Research UK.

 

Only applications received before 12 midday on Thursday, 23 April 2026 will be considered. Please quote 183381 on all correspondence.