The University of Oxford is a stimulating work environment, which enjoys an international reputation as a world-class centre of excellence. Our research plays a key role in tackling many global challenges, from reducing our carbon emissions to developing vaccines during a pandemic.

 

The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching.

 

The Botnar Institute for Musculoskeletal Sciences enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research.

 

The UK Research and Innovation Musculoskeletal Functional Genomics Initiative Cluster (MSK Cluster) is led by Professor Dominic Furniss and began in May 2024. This is one of four Functional Genomics clusters in the UK that have been funded by UKRI to accelerate the translation of genetic results into tangible benefits for patients. Alongside the core aim to deliver improved treatments for musculoskeletal disease, there is also a strong commitment to training and public engagement.  

 

 

As an employer, we genuinely care about our employees’ wellbeing and this is reflected in the range of benefits that we offer including: 

 

•    An excellent contributory pension scheme 

•    38 days annual leave 

•    A comprehensive range of childcare services 

•    Family leave schemes 

•    Cycle loan scheme 

•    Discounted bus travel and Season Ticket travel loans 

•    Membership to a variety of social and sports clubs 

 

 

We are seeking an experienced and enthusiastic individual for the role of research technician specialising in next generation sequencing and imaging. Your work will help to accelerate translation of genetic findings to treat four key musculoskeletal diseases: osteoarthritis, carpal tunnel syndrome, frozen shoulder, and Dupuytren disease. In this role you will be responsible for the development and implementation of standardized protocols for patient blood and tissue sample processing for nucleic acid extraction or imaging. You will be liaising with teams across the Functional Genomics setting to ensure adequate samples are available for sequencing as well as teaching experimental techniques to new laboratory members and providing supervision of new lab members within the laboratory. You will be responsible for managing DNA and RNA extraction from human blood and tissue samples prior to genotyping, methylation and transcriptome analysis. 

 

 

You will hold a BSc or MSc in biological science or equivalent experience together with previous laboratory experience of methods including nucleic acid extraction from tissues and immunohistochemistry as well as of next generation sequencing library preparation. You will have the ability to work co-operatively as part of a team, as well as independently while taking personal responsibility for assigned tasks. You will demonstrate basic computing skills, including use of Microsoft Word and Excel together with the ability to learn and develop new techniques, and to troubleshoot them. You will be able to clearly demonstrate the ability to keep extensive and detailed records that comply with necessary legislation (e.g. the human tissue act). Experience in training individuals in laboratory techniques as well as experience of basic analysis of sequencing or spatial mapping data are desirable.

 

 

You will be required to upload a covering letter/supporting statement, CV and the details of two referees as part of your online application. Please quote 186906 in all correspondence. 

 

The closing date for applications is 12pm 13 July 2026.

 

Interviews will take place during week commencing  27 July 2026 and will be hybrid. 

 

 

The University of Oxford is a stimulating work environment, which enjoys an international reputation as a world-class centre of excellence. Our research plays a key role in tackling many global challenges, from reducing our carbon emissions to developing vaccines during a pandemic.

 

The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching. The Botnar Research Centre enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research.

 

Oxford Translational Myeloma Centre (OTMC), NDORMS, is based at the Botnar Institute and is dedicated to advancing personalized care in Multiple Myeloma and related plasma cell dyscrasias towards achieving better patient outcome and cure. OTMCbio is a new Biobanking protocol, whose purpose is to collect and store samples from patients, and support the translational programs of OTMC.

 

 

As an employer, we genuinely care about our employees’ wellbeing and this is reflected in the range of benefits that we offer including: 

 

•               An excellent contributory pension scheme 

•               38 days annual leave 

•               A comprehensive range of childcare services 

•               Family leave schemes 

•               Cycle loan scheme 

•               Discounted bus travel and Season Ticket travel loans 

•               Membership to a variety of social and sports clubs 

•               This role also offers the opportunity for hybrid working 

 

 

The postholder will be a member of the Biobank team led by the Chief Investigator (Professor Anjan Thankurta) and will be based in our laboratory at Botnar Institute.  The postholder will process samples for OTMC biobank, monitor results to spot discrepancies and propose refinements and re-run experiments where necessary, ensure the smooth day-to-day running of the laboratory, e.g. by ensuring equipment is functioning and monitoring and ordering stock as necessary. They will also ensure that Biobank operations are in accordance with SOPs and all regulatory and research governance requirements (including the Human Tissue Act), as well as check and record the identity and quality of samples on receipt and throughout the process to long-term storage. Enter data into the tissue bank database.

  
 

 

You will hold a first degree in Healthcare/ Management/ Science-related subject or relevant equivalent experience. You will also have previous experience of working in a laboratory environment and handling of human samples (blood, bone marrow etc.). Experience of sample processing in management research studies or clinical trial, as well as hands-on experience of tissue bank techniques, is desirable.

 
 

 

The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.
 

Applications for this vacancy should be made online and must include a CV and a supporting statement explaining how you meet the selection criteria, using examples of your skills and experience.
 

Interviews will take place during week commencing 27 July 2026 and will be online/in person.

 

Please quote reference 187158 in all correspondence.

 

The University of Oxford is a stimulating work environment, which enjoys an international reputation as a world-class centre of excellence. Our research plays a key role in tackling many global challenges, from reducing our carbon emissions to developing vaccines during a pandemic.

 

The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching.

 

The Botnar Institute for Musculoskeletal Sciences enables and encourages research and education into the causes of musculoskeletal disease and their treatment. The Centre provides world-class facilities for scientists in the field of musculoskeletal research.

 

The Karedla Group develops next-generation optical microscopy and spectroscopy methods to uncover the physical principles governing immune-cell function. The laboratory brings together technology development at the Rosalind Franklin Institute with immunology at the Botnar Institute, supported by established collaborations across NDORMS and with research groups throughout the UK.  

 

 

As an employer, we genuinely care about our employees’ wellbeing and this is reflected in the range of benefits that we offer including: 

 

•    An excellent contributory pension scheme 

•    38 days annual leave 

•    A comprehensive range of childcare services 

•    Family leave schemes 

•    Cycle loan scheme 

•    Discounted bus travel and Season Ticket travel loans 

•    Membership to a variety of social and sports clubs 

 

 

We are seeking a Postdoctoral Researcher to participate in research in the Quantitative Immunodynamics Laboratory led by Dr. Narain Karedla as a part of an ERC Starting Grant project MIETEN (Metal-Induced Energy Transfer based Electrometry and Nanometry). In this role, you will contribute to the ERC-funded MIETEN programme by developing and applying quantitative fluorescence microscopy and spectroscopy methods for single-molecule charge measurements, and nanoscale membrane electrostatics. You will also adapt existing scientific techniques and develop new experimental techniques to investigate how molecular and membrane electrostatics regulate immune-cell signalling and immune cell - target cell interactions, using engineered substrates, electroactive biointerfaces, and membrane-mimetic systems. This position involves the use of specialist laboratory equipment, including advanced fluorescence microscopy and spectroscopy platforms such as the PicoQuant Luminosa, to generate, analyse and interpret imaging, fluorescence lifetime, single-molecule, correlation spectroscopy and other biophysical data. 

 

You will hold a PhD/DPhil (or near completion) in physics, biophysics, physical chemistry, nanoscience, bioengineering or a closely related discipline together with a strong background in quantitative fluorescence microscopy or spectroscopy, with experience in methods related to single-molecule, or membrane biophysics. You will have demonstrable experience in developing, fabricating and characterising, for example, engineered substrates, nanoscale devices, electroactive biointerfaces, or thin-film platforms for optical, electrochemical, or biological measurements. You will also have the ability to design, plan, and independently manage academic research and associated activities as well as evidence of research productivity appropriate to career stage, including publications, preprints, conference presentations, or other relevant research outputs. Experience with FCS, FLCS, single-molecule fluorescence, super-resolution microscopy, or photon-counting/TCSPC methods is desirable. 

 

 

You will be required to upload a covering letter/supporting statement, CV and the details of two referees as part of your online application. Please quote 186733 in all correspondence. 

 

The closing date for applications is 12pm 3 July 2026.

 

Interviews will take place during week commencing  20 July 2026 and will be hybrid.