In this role, you will help deliver interventional gastroenterology studies including identifying and recruiting patients, providing clinical care in accordance with trial protocols, and collecting and processing blood and tissue samples for downstream single-cell and bulk RNA analysis, transcriptomics and proteomics. You will work closely with wet-lab scientists, bioinformaticians, clinical colleagues and the industry partners to generate insights as the trial progresses. You will also contribute to data analysis, research papers, conference abstracts and grant applications, while supporting the accurate documentation and regulatory standards required for clinical research.

 

It is essential that you hold a Bachelor’s degree in Medicine and be a UK GMC-registered medical practitioner with experience working full time as a doctor within the NHS. You will need excellent communication, interpersonal and organisational skills, together with the ability to work effectively both independently and as part of a multidisciplinary team. A methodical approach to data collection, an understanding of data protection and relevant professional guidelines, and the ability to manage multiple projects are also essential. Experience in gastroenterology, clinical trials or research, MRCP or equivalent, and an understanding of research methodology would be advantageous.

 

The post also offers significant scope for research and professional development. You will be encouraged to develop an area of your own interest and may have the opportunity to work towards a higher degree, such as a DPhil or MSc, with potential funding available through the industry collaboration. Training and research opportunities within the Clinical Trials Unit and wider translational research programme will further support your development during the three-year appointment.

 

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

 

This position is offered full time on a fixed term contract for 3 years and is funded by Johnson and Johnson.

 

Only applications received before 12 midday on 12 November 2026 will be considered. Please quote 188948 on all correspondence.

 

You will be responsible for managing your own research and laboratory activities, planning and coordinating experimental work to support the successful delivery of defined projects. You will develop, optimise and apply analytical protocols and experimental techniques, using specialist knowledge to test hypotheses and refine research approaches. As a Postdoctoral Research Assistant, you will use scientific laboratory equipment, analysis and interpret experimental data, and collaborate with colleagues to provide advice on research methods and techniques. You will contribute to research publications, including peer-reviewed journal articles, book chapters and reviews, and communicate findings through national conferences and seminars. You will also support collaborative projects, organise and delegate activities where appropriate. Coaching colleagues in specialist methodologies and contribute to the Department and University’s public engagement and widening access activities is also a key part to the role.

 

It is essential that you hold a relevant PhD/DPhil, or equivalent qualification in viral immunology, cellular immunology or a related subject. Having demonstrable experience of conducting immunological or infectious disease research in a research laboratory is a must. It is essential to have sufficient specialist knowledge to develop, optimise and apply experimental research methodologies. You must also hold the ability to independently plan and organise experimental work and contribute effectively to the delivery of a research project.

 

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

 

This position is offered full time on a fixed term contract for 24 months and is funded by UKRI - MRC.

 

Only applications received before 12 midday on 11 November 2026 will be considered. Please quote 188876 on all correspondence.

 

 

This is an exciting opportunity arising from a major new grant of £6.7 million from the Advanced Research and Invention Agency (ARIA) – a UK government funding agency. You will work with Professor Chris O'Callaghan and Dr Nathali Flores-Fernández on further development and application of our DNA assembly technology to create synthetic organelle genomes. This synthetic biology project aims to move rapidly to translation with real-world testing of synthetic chloroplast genomes in relevant crop plants including potato (Solanum tuberosum) and wheat (Triticum aestivum) with Professors Steve Kelly and Francesco Licausi. Synthetic genomes will incorporate multiple variants that have arisen independently in nature and have potential to improve desirable properties, such as resistance to disease and environmental/ climate stress. This is a great opportunity to develop skills in state-of-the-art techniques while working on a project with major potential for high impact.

 

Your primary role will be to assist in planning and to carry out experiments and analyse the results within Professor Chris O’Callaghan’s laboratory (https://www.chg.ox.ac.uk/research/research-groups/ocallaghan-group-1). This will involve molecular biology and biochemistry to undertake DNA assembly including generating constructs and testing new approaches. This is a translational project to further develop and apply technology that we have invented to assemble large DNA molecules of any sequence with ease. Using this technology, it is possible to rapidly and simply assemble DNA molecules up to hundreds of thousands of base-pairs in length. We have progressively improved and simplified this technology which uses recombinant DNA methylases as published in PubMed 40548934, PubMed 41858718, and PubMed 38270650. There may also be some expression and purification of recombinant enzymes such as methylases. There is also scope for some bioinformatic/ computational analysis but this is primarily a laboratory-based post. The laboratory is well equipped for this work and for testing the function of assembled DNA molecules. The project will enjoy a high level of funding and if successful there is potential for a further 2 or 3-year phase of funding to be awarded. The project collaborators include Professor Francesco Licausi and Professor Steve Kelly.

 

You will be responsible for managing your own academic research and administrative activities, adapting existing and developing new scientific techniques and experimental protocols.

 

It is essential that you hold a PhD/DPhil (or be close to completion) in a relevant discipline such as molecular/synthetic biology, biochemistry, biotechnology or related subject. You will also have proven experience and confidence in molecular cloning and DNA assembly, working with and extraction of long DNA molecules, bacterial cultures, and recombinant protein production and purification.

 

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.  

This position is offered full time on a fixed term contract until 31 May 2028 and is funded by the Advanced Research and Innovation Agency (ARIA).

 

Only applications received before 12 midday on 4 November 2026 will be considered. Please quote 188879 on all correspondence.

 

Informal enquiries should be addressed to Prof Chris O’Callaghan (chris.ocallaghan@ndm.ox.ac.uk).

 

You will lead bioinformatic and statistical analysis of large-scale genomic and transcriptomic datasets from human samples, cell lines, and mouse models; developing and implementing novel analytical approaches where appropriate; leading the research project; collaborating with internal and external researchers; contributing to the supervision of MSc and PhD students; maintaining high standards of data quality, integrity, and documentation; disseminating findings through publications, presentations, and conferences; engaging with patient advocacy groups; and supporting public engagement and outreach activities. This is an exciting opportunity to contribute to pioneering rare disease research within a highly collaborative environment and to develop your own scientific profile within a world-leading therapeutic genomics programme.

 

It is essential that you have a PhD/DPhil (or are close to completion) in a relevant field such as genomics, genetics, bioinformatics, biostatistics, statistics together with a track record of contributing to peer-reviewed publications and presenting research findings at seminars, conferences, and scientific meetings. Proficiency in programming languages such as R and/or Python is required, alongside the ability to independently manage day-to-day research activities, take ownership of projects, and deliver high-quality outputs to agreed deadlines. You should have experience working collaboratively within multidisciplinary teams and possess excellent written and verbal communication skills, including the ability to prepare publications, create clear and informative data visualisations, and present research to both specialist and non-specialist audiences.

 

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

 

This position is offered full time on a fixed term contract for two years.

 

Only applications received before 12 midday on Thursday 29 October 2026 will be considered. Please quote 187206 on all correspondence.