We are seeking a talented, ambitious and highly skilled postdoctoral researcher to join a dynamic research group investigating the human epigenome and its relationship with diet, genetics, transcriptomics, and multiple clinically relevant traits. The post is funded via a collaborative grant led by us at KCL, funded by HDHL JPI and the post holder will therefore also join our established international multi-disciplinary consortium in nutri-genomics.
The project investigates causal impacts of dietary intake on epigenetic regulation of gene function across tissues, and their impact on subsequent cardio-metabolic health outcomes - building on previous work from our research group and consortium partners (Wahl et al. 2017 Nature). The focus is on computational analysis of epigenetic data from: (i) targeted postprandial and nutritional intervention studies that tackle the causal relationships between diet, epigenetic modifications and gene function, in combination with (ii) state-of-the-art analyses to characterize the links between diet, epigenetics, and cardio-metabolic health in extensively studied cohorts. The project utilizes unique multi-dimensional datasets from nutrition trials and international cohorts, including TwinsUK with over 1,500 deeply phenotyped twins with epigenetics, as well as whole genome sequence, transcriptomic, metabolomic, and gut microbiome profiles in a sample subset. The ideal candidate should have a strong background in one of the following fields: epigenomics, transcriptomics, genomics, nutri-genomics, statistical genetics or genetic epidemiology. The post is available for 24 months in the first instance.
This post will be offered on a fixed-term contract for 24 months.
This is a full-time post
The selection process will include a panel interview.
To apply, please register with the King's College London application portal and complete your application online.